产品
编 号:F750227
分子式:C24H46N2O3
分子量:410.63
产品类型
结构图
CAS No: 2240164-55-8
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产品详情
生物活性:
Oleoyl-D-lysine is a selective Glycine Transporter-2 (GlyT2) inhibitor based on lipid. Oleoyl-D-lysine reverses neuropathic pain in mice, shows antidrowsiness effect on chronic neuropathic pain. Oleoyl-D-lysine is safe and effective without respiratory depression.
体内研究:
Oleoyl-D-lysine effectively reverses neuropathic pain in a mouse model of chronic neuropathic (chronic constriction injury) pain, reaching a peak analgesic dose of 30 mg/kg without causing respiratory depression; resultig mild side effects at 100 mg/kg without causing convulsions.