产品
编 号：F750120
分子式：C19H16Cl2FN5OS
分子量：452.33
分子式：C19H16Cl2FN5OS
分子量：452.33
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CAS No: 2230874-00-5
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生物活性：
KRAS inhibitor-12 (compound 6-1) is a potent KRAS G12C inhibitor with an IC50 of 0.537 μM. KRAS inhibitor-12 shows p-ERK inhibition activities with IC50s of 1.3, 3.7 μM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-12 has the potential for the research of pancreatic, colorectal, and lung cancers.
KRAS inhibitor-12 (compound 6-1) is a potent KRAS G12C inhibitor with an IC50 of 0.537 μM. KRAS inhibitor-12 shows p-ERK inhibition activities with IC50s of 1.3, 3.7 μM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-12 has the potential for the research of pancreatic, colorectal, and lung cancers.
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