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编 号:F750119
分子式:C25H19ClFN3O2S
分子量:479.95
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KRAS inhibitor-13 (compound 5-6) is a potent KRAS G12C inhibitor with an IC50 of 0.883 μM. KRAS inhibitor-13 shows p-ERK inhibition activities with IC50s of 5.9, >100 μM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-13 has the potential for the research of pancreatic, colorectal, and lung cancers.
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