产品
编 号：F750117
分子式：C20H15ClF3N3O2S
分子量：453.87
分子式：C20H15ClF3N3O2S
分子量：453.87
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CAS No: 2230873-66-0
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生物活性：
KRAS inhibitor-18 (compound 3-10) is a potent KRAS G12C inhibitor with an IC50 of 4.74 μM. KRAS inhibitor-18 shows p-ERK inhibition activities with IC50s of 66.4, 11.1 μM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-18 has the potential for the research of pancreatic, colorectal, and lung cancers.
KRAS inhibitor-18 (compound 3-10) is a potent KRAS G12C inhibitor with an IC50 of 4.74 μM. KRAS inhibitor-18 shows p-ERK inhibition activities with IC50s of 66.4, 11.1 μM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-18 has the potential for the research of pancreatic, colorectal, and lung cancers.
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