产品
编 号:F750116
分子式:C21H18Cl2FN3O2S
分子量:466.36
产品类型
结构图
CAS No: 2230873-65-9
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生物活性:
KRAS inhibitor-17 (compound 3-9) is a potent KRAS G12C inhibitor with an IC50 of 3.37 μM. KRAS inhibitor-17 shows p-ERK inhibition activities with IC50s of 9.25, >33.3 μM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-17 has the potential for the research of pancreatic, colorectal, and lung cancers.