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编 号:F749972
分子式:C23H31N7O
分子量:421.54
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC50 value of 7 nM for human TLR9. TLR9-IN-1 can be used for researching diseases associated with undesirable immune response.

体外研究:
TLR9-IN-1 (compound no.29) (0-10 μM; 24 h) exhibits moderately inhibitory activity against IL-1b with an IC50 of 1.61 μM in human monocytes (co-incubated with TLR8 agonist ORN8L, RNA oligonucleotide).
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