产品
编 号：F749910
分子式：C13H13F7N4O7
分子量：470.25
分子式：C13H13F7N4O7
分子量：470.25
产品类型
规格
价格
是否有货
结构图
CAS No: 2222067-23-2
产品详情
生物活性：
Neuraminidase-IN-13 (Compound 10) is a neuraminidase inhibitor with antiviral activity and low cytotoxicity. Neuraminidase-IN-13 significantly inhibits NDV infection of Vero cells by preventing the release of viral particles from infected cells. Neuraminidase-IN-13 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
体外研究：
Neuraminidase-IN-13 抑制 NDV La Sota 菌株中的斑块形成，IC50 值为 0.06 μM。Neuraminidase-IN-13 抑制病毒增殖，IC50 为 0.04 μM。Neuraminidase-IN-13 对细胞无毒性，CC50值大于2500 μM。Neuraminidase-IN-13 抑制病毒结合 Vero 细胞，IC50 为 4 μM。Neuraminidase-IN-13 抑制 Vero 细胞中病毒释放，IC50 值为 0.09 μM。
Neuraminidase-IN-13 (Compound 10) is a neuraminidase inhibitor with antiviral activity and low cytotoxicity. Neuraminidase-IN-13 significantly inhibits NDV infection of Vero cells by preventing the release of viral particles from infected cells. Neuraminidase-IN-13 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
体外研究：
Neuraminidase-IN-13 抑制 NDV La Sota 菌株中的斑块形成，IC50 值为 0.06 μM。Neuraminidase-IN-13 抑制病毒增殖，IC50 为 0.04 μM。Neuraminidase-IN-13 对细胞无毒性，CC50值大于2500 μM。Neuraminidase-IN-13 抑制病毒结合 Vero 细胞，IC50 为 4 μM。Neuraminidase-IN-13 抑制 Vero 细胞中病毒释放，IC50 值为 0.09 μM。
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备