产品
编 号:F749888
分子式:C26H27NO4
分子量:417.5
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
POLA1 inhibitor 1 (Compound 12) is an orally active POLA1 inhibitor. POLA1 inhibitor 1 shows antitumor activity against several tumor histotypes and Adarotene-resistant cell line.

体内研究:
POLA1 inhibitor 1 (Compound 12) (15 mg/kg and 50 mg/kg) displays a significantly antitumor effect in HT-29 and MM487 xenografts.
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