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编 号:F749880
分子式:C9H10FN3O3
分子量:227.19
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生物活性:
L-2'-Fd4C, is an l-nucleoside analogue. L-2'-Fd4C has anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity.

体内研究:
L-2'-Fd4C (100 mg/kg; i.p.; daily, for 7 d) has antihepadnavirus potency in HBV-transgenic mice.Animal Model:HBV-transgenic mice
Dosage:100 mg/kg
Administration:Intraperitoneal injection; daily, for 7 days
Result:Had a reduction of HBV levels in their blood comparable to that produced by Lamivudine (HY-B0250).

体外研究:
L-2'-Fd4C (0-10 μM; 9 d; HepG2-2.2.15 cells) inhibits anti-hepatitis B virus (HBV) replication with an EC50 value of 0.002 μM.
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