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编 号:F749878
分子式:C34H34FN3O6S
分子量:631.71
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生物活性:
PCSK9 ligand 1 is a selective proprotein convertase substilisin-like/kexin type 9 (PCSK9) ligand. PCSK9 ligand 1 does not affect PCSK9 function.

体外研究:
Biphenyl acid PCSK9 ligand 1 (compound 9) binds to and thermally stabilizes PCSK9 in a complex environment such as Huh7 lysate.PCSK9 ligand 1 (compound 9), withhigh affinity for recombinant PCSK9 and target engagement in cell lysate, could be used as a recruiting element to promote the selective degradation of PCSK9.
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