产品
编 号:F749826
分子式:C33H43N7O9
分子量:681.74
产品类型
结构图
CAS No: 220701-06-4
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产品详情
生物活性:
Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing.
体外研究:
Fmoc-Ala-Glu-Asn-Lys-NH2 拮抗 AEP 对 APP 的加工,而其他小分子抑制剂和无活性肽 AEQK 则没有作用。