产品
编 号：F749808
分子式：C13H13ClFN5O7
分子量：405.72
分子式：C13H13ClFN5O7
分子量：405.72
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结构图
CAS No: 2204291-78-9
产品详情
生物活性：
BK50164 is a potent CD73 inhibitor with an IC50 value of 13.089 μM. BK50164 binds to CD99 with a KD value of 1.5 μM. BK50164 shows antiproliferative activity. BK50164 induced Apoptosis and cell cycle arrest at Sub-G1 phase.
体外研究：
BK50164 (0-400 μM；48 小时) 显示抗增殖活性，对 A4573, TC-32, TC-71, Saos-2, U-2 OS 细胞的 IC50 值分别为35.8, 34.28, 5.17, ≥400, ≥400 μM。BK50164 (4-16 μM; 48 h) 诱导细胞凋亡和细胞周期停滞在 Sub-G1 期。
BK50164 is a potent CD73 inhibitor with an IC50 value of 13.089 μM. BK50164 binds to CD99 with a KD value of 1.5 μM. BK50164 shows antiproliferative activity. BK50164 induced Apoptosis and cell cycle arrest at Sub-G1 phase.
体外研究：
BK50164 (0-400 μM；48 小时) 显示抗增殖活性，对 A4573, TC-32, TC-71, Saos-2, U-2 OS 细胞的 IC50 值分别为35.8, 34.28, 5.17, ≥400, ≥400 μM。BK50164 (4-16 μM; 48 h) 诱导细胞凋亡和细胞周期停滞在 Sub-G1 期。
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