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编 号:F749577
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规格
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1mg
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5mg
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生物活性:
Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs.

体内研究:
Bedinvetmab (0.5-1 mg/kg; s.c. for 28 d) 减轻与犬骨关节炎相关的疼痛。Bedinvetmab (1 mg/kg; s.c. monthly; 3× and 10× dose multiples) 与 Carprofen (HY-B1227) 共同给药,在正常实验室比格犬中耐受性良好。
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