产品
编 号：F749539
分子式：C25H31N7OS
分子量：477.62
分子式：C25H31N7OS
分子量：477.62
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 2170136-86-2
产品详情
生物活性：
GSK3735967 is an selective, reversible, non-nucleoside inhibitor of DNMT1 with an IC50 value of 40 nM. GSK3735967 contains a planar dicyanopyridine core that can specifically embed DNMT1 bound hemimethylated CpG dinucleotides. GSK3735967 has three binding sites, one of which can bind to histone H4K20me3.
体外研究：
GSK3735967 (0.1-10000 nM) 以剂量依赖性方式抑制 DNMT1 的活性。
GSK3735967 is an selective, reversible, non-nucleoside inhibitor of DNMT1 with an IC50 value of 40 nM. GSK3735967 contains a planar dicyanopyridine core that can specifically embed DNMT1 bound hemimethylated CpG dinucleotides. GSK3735967 has three binding sites, one of which can bind to histone H4K20me3.
体外研究：
GSK3735967 (0.1-10000 nM) 以剂量依赖性方式抑制 DNMT1 的活性。
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备