产品
编 号：F749436
分子式：C19H29ClN2O3
分子量：368.9
分子式：C19H29ClN2O3
分子量：368.9
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2162149-24-6
产品详情
生物活性：
Sonlicromanol (KH176) hydrochloride, a chemical entity derivative of Trolox, is a blood-brain barrier permeable ROS-redox modulator. Sonlicromanol (KH176) hydrochloride is used in the study for mitochondrial disorders.
体内研究：
Sonlicromanol (KH176) hydrochloride maintains microstructural coherence in the brain of Ndufs4?/? mice.Animal Model:Ndufs4?/? mice (Leigh Disease model).
Dosage:10?mg/kg.
Administration:IP, daily (PD14-PD45, 32 days).
Result:Significantly improve rotarod and gait performance and reduced the degeneration of retinal ganglion cells.Resulted in statistically significantly higher FA values in the external capsule and a similar trend was found in the cerebral peduncle.
Sonlicromanol (KH176) hydrochloride, a chemical entity derivative of Trolox, is a blood-brain barrier permeable ROS-redox modulator. Sonlicromanol (KH176) hydrochloride is used in the study for mitochondrial disorders.
体内研究：
Sonlicromanol (KH176) hydrochloride maintains microstructural coherence in the brain of Ndufs4?/? mice.Animal Model:Ndufs4?/? mice (Leigh Disease model).
Dosage:10?mg/kg.
Administration:IP, daily (PD14-PD45, 32 days).
Result:Significantly improve rotarod and gait performance and reduced the degeneration of retinal ganglion cells.Resulted in statistically significantly higher FA values in the external capsule and a similar trend was found in the cerebral peduncle.
产品资料
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