产品
编 号：F749248
分子式：C28H33ClN6O3
分子量：537.05
分子式：C28H33ClN6O3
分子量：537.05
产品类型
规格
价格
是否有货
结构图
CAS No: 2136270-68-1
产品详情
生物活性：
SPOP-IN-6b hydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM.
体内研究：
SPOP-IN-6b (40-80 mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) can slow down the growth of tumour by suppressing SPOP.
体外研究：
SPOP-IN-6b shows IC50s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2 and 786-0 cells.SPOP-IN-6b (0.1-3.0 μM; 10 hours) can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content.
SPOP-IN-6b hydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM.
体内研究：
SPOP-IN-6b (40-80 mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) can slow down the growth of tumour by suppressing SPOP.
体外研究：
SPOP-IN-6b shows IC50s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2 and 786-0 cells.SPOP-IN-6b (0.1-3.0 μM; 10 hours) can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content.
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