产品
编 号：F749241
分子式：C28H26ClF3N2O6
分子量：578.96
分子式：C28H26ClF3N2O6
分子量：578.96
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2135640-93-4
产品详情
生物活性：
(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against a panel of 21 clinical isolates. (+)-JNJ-A07 has a favourable pharmacokinetic profile that results in outstanding efficacy against dengue virus infection in mouse infection models.
体外研究：
(+)- JNJ-A07 具有高耐药屏障，可通过阻断两种病毒蛋白 (NS3 和 NS4B) 之间的相互作用来阻止病毒复制复合物的形成。
(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against a panel of 21 clinical isolates. (+)-JNJ-A07 has a favourable pharmacokinetic profile that results in outstanding efficacy against dengue virus infection in mouse infection models.
体外研究：
(+)- JNJ-A07 具有高耐药屏障，可通过阻断两种病毒蛋白 (NS3 和 NS4B) 之间的相互作用来阻止病毒复制复合物的形成。
产品资料
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