产品
编 号：F749051
分子式：C19H27N3
分子量：297.44
分子式：C19H27N3
分子量：297.44
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CAS No: 2103079-87-2
产品详情
生物活性：
UHMCP1 is a chemical probe of U2AF homology motifs (UHM) with a Kd of 79 μM. UHMCP1 prevents the SF3b155/U2AF65 interaction, impacts RNA splicing and cell viability. UHMCP1 has potential anticancer properties.
体外研究：
UHMCP1 (25-400 μM) reduces the binding of purified U2AF65 to SF3b155 by 75%, exhibiting a simple, non-cooperative binding mode with Kd around 30 μM for U2AF65.UHMCP1 (0-200 μM; 24 h) exhibits a certain effect on cell viability of HEK293.
UHMCP1 is a chemical probe of U2AF homology motifs (UHM) with a Kd of 79 μM. UHMCP1 prevents the SF3b155/U2AF65 interaction, impacts RNA splicing and cell viability. UHMCP1 has potential anticancer properties.
体外研究：
UHMCP1 (25-400 μM) reduces the binding of purified U2AF65 to SF3b155 by 75%, exhibiting a simple, non-cooperative binding mode with Kd around 30 μM for U2AF65.UHMCP1 (0-200 μM; 24 h) exhibits a certain effect on cell viability of HEK293.
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