产品
编 号:F748968
分子式:C28H29N3O5
分子量:487.56
产品类型
结构图
CAS No: 2098191-54-7
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生物活性:
rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A?inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex.