产品
编 号:F748967
分子式:C108H182N44O25S2
分子量:2561.02
产品类型
结构图
CAS No: 2098181-84-9
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产品详情
生物活性:
KRpep-2d is a potent K-Ras inhibitor and inhibits proliferation of K-Ras-driven cancer cells. KRpep-2d can be used for cancer research.
体外研究:
KRpep-2d has cyclic structure with importance for K-Ras inhibitory activity. Leu77 , Ile9 and Asp12 are critical amino acid residues for the K-Ras inhibitory activity of KRpep-2d. KRpep-2d (10-30 μM) has inhibitory activity of A427 cells with the proliferation rates of 68.3% (10 μM) and 48.3% (10 μM).