产品
编 号：F748873
分子式：C39H28F5NO18
分子量：893.63
分子式：C39H28F5NO18
分子量：893.63
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规格
价格
是否有货
结构图
CAS No: 209540-67-0
产品详情
生物活性：
FDGlcU can be used as a fluorescent probe for non-invasively image with a high level of fluorescent activity. FDGlcU is non-fluorescent when the fluorescein is conjugated with two mono-glucuronides (Ex/Em=480/514 nm).
体内研究：
FDGlcU (7.3 μM/kg) can be used for in vivo time-lapse imaging of bacterial βG activity. FDGlcU can be used for real-time imaging in vivo.Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).Whole-body imaging for intestinal βG activity:1. On the day of imaging, gavage mice with 50 μL of DDW, FDGlcU (7.3 μM/kg), and fluorescein (7.3 μM/kg). 2. Anesthetize mice with isoflurane and whole-body optical images using an IVIS spectrum optical imaging system with a GFP filter set. 3. In biodistribution study, mice are sacrificed 3 hour after gavaged with FDGlcU or fluorescein (λex =480 nm, λem =514 nm).
体外研究：
FDGlcU (0.5 μg/mL; 12 h) shows enzymatic activity and inhibits βG activity in live bacteria.
FDGlcU can be used as a fluorescent probe for non-invasively image with a high level of fluorescent activity. FDGlcU is non-fluorescent when the fluorescein is conjugated with two mono-glucuronides (Ex/Em=480/514 nm).
体内研究：
FDGlcU (7.3 μM/kg) can be used for in vivo time-lapse imaging of bacterial βG activity. FDGlcU can be used for real-time imaging in vivo.Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).Whole-body imaging for intestinal βG activity:1. On the day of imaging, gavage mice with 50 μL of DDW, FDGlcU (7.3 μM/kg), and fluorescein (7.3 μM/kg). 2. Anesthetize mice with isoflurane and whole-body optical images using an IVIS spectrum optical imaging system with a GFP filter set. 3. In biodistribution study, mice are sacrificed 3 hour after gavaged with FDGlcU or fluorescein (λex =480 nm, λem =514 nm).
体外研究：
FDGlcU (0.5 μg/mL; 12 h) shows enzymatic activity and inhibits βG activity in live bacteria.
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