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编 号:F748611
分子式:C27H32N8O2
分子量:500.6
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CAS No: 2064269-82-3
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YK-029A is an orally active inhibitor of mutant EGFR,targeting to both the T790M mutations (EGFRT790M) and exon 20 insertion of EGFR (EGFRex20ins). YK-029A exhibits significant antitumor activity,and results tumor regression in EGFRex20ins-driven PDX models.