产品
编 号：F748332
分子式：C19H20N2O4
分子量：340.37
分子式：C19H20N2O4
分子量：340.37
产品类型
规格
价格
是否有货
结构图
CAS No: 2011784-92-0
产品详情
生物活性：
Tubulin polymerization-IN-37 is a tubulin polymerization inhibitor (IC50: 2.3 μΜ). Tubulin polymerization-IN-37 binds to the colchicine site of tubulin and inhibits colchicine binding. Tubulin polymerization-IN-37 can be used in the research of cancers, such as lymphomas.
体外研究：
Tubulin polymerization-IN-37 (compound 2f, 1 μΜ, 72 h) inhibits proliferation of lymphoma cells below 50%.Tubulin polymerization-IN-37 (50 and 500 nM, 24-72 h) induces cell apoptosis and arrests cell in G2/M phase in VL51 and MINO cells.Tubulin polymerization-IN-37 (5 μΜ) inhibits colchicine binding to tubulin by 80%.Tubulin polymerization-IN-37 shows cytotoxicity against MCF-7 cells (IC50: 0.21 μΜ).
Tubulin polymerization-IN-37 is a tubulin polymerization inhibitor (IC50: 2.3 μΜ). Tubulin polymerization-IN-37 binds to the colchicine site of tubulin and inhibits colchicine binding. Tubulin polymerization-IN-37 can be used in the research of cancers, such as lymphomas.
体外研究：
Tubulin polymerization-IN-37 (compound 2f, 1 μΜ, 72 h) inhibits proliferation of lymphoma cells below 50%.Tubulin polymerization-IN-37 (50 and 500 nM, 24-72 h) induces cell apoptosis and arrests cell in G2/M phase in VL51 and MINO cells.Tubulin polymerization-IN-37 (5 μΜ) inhibits colchicine binding to tubulin by 80%.Tubulin polymerization-IN-37 shows cytotoxicity against MCF-7 cells (IC50: 0.21 μΜ).
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备