产品
编 号:F748329
分子式:C26H31N5O4S
分子量:509.62
产品类型
结构图
CAS No: 2011756-99-1
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产品详情
生物活性:
Antitumor Agent-71 is an antiproliferative activity antitumor agent and against tumor cell lines with IC50 values ranging from 3.98-15.70 μM. Antitumor Agent-71 is an antitumor agent that can inhibit tubulin polymerization.
体内研究:
Antitumor agent-71 (10-20 mg/kg; intravenous injection; twice a day; 20 days) shows inhibitory effects and inhibits HepG2 cell line in nude mice.Animal Model:HepG2 model BALB/c nude mice
Dosage:10mg/kg, 20mg/kg
Administration:Intravenous injection; twice a day; 20 days
Result:Inhibited tumor growth in a dose-dependent manner.
体外研究:
Antitumor agent-71 (0.002-20 μM; 48 hours) inhibits the cell line HepG2, MCF-7, MIA PaCa-2, and Bel-7402 growth in a dose-dependent manner.