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编 号:F748260
分子式:C14H8Cl2N4O4S
分子量:399.21
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生物活性:
HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows anti-influenza virus activity in MDCK cells, with EC50 values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively.

体外研究:
HSP90-IN-14 (compound 4) (50 μM) inhibits influenza virus-induced cytopathic effect at non-toxic concentrations.
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