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编 号:F748130
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CAS No: 1965342-41-9
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生物活性:
ODN 105871, a G-modified inhibitory oligonucleotide (INH-ODN), is a selective TLR7 inhibitor. ODN 105871 can be uesd for inflammatory immune responses research.
体外研究:
ODN 105871 potently inhibits the TLR7-induced TNF-α response in bone marrow-derived macrophages (BMDMs).In case of Imiquimod-stimulated B cells, ODN 105871 reduces the ATP content to the pretreatment level.