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编 号:F748129
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生物活性:
ODN 105870, a G-modified inhibitory oligonucleotide (INH-ODN), is a selective TLR7 inhibitor. ODN 105870 can be uesd for inflammatory immune responses research.

体外研究:
ODN 105870 potently inhibits the TLR7-induced TNF-α response in bone marrow-derived macrophages (BMDMs).In case of Imiquimod-stimulated B cells, ODN 105870 (10 μM) reduces the ATP content to the pretreatment level.
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