产品
编 号:F010131
分子式:C14H16O4S
分子量:280.34
产品类型
结构图
CAS No: 101973-77-7
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产品详情
生物活性:
Esonarimod (KE-298) is an antirheumatic agent.
体内研究:
After repeated oral administration of Esonarimod (14C-KE-298), the radioactivity decreases rapidly and no tendency towards accumulation is found.
体外研究:
Esonarimod (KE-298) (10 to 300 μg/mL) suppresses the production of NO by RAW264.7 cells in a dose dependent manner. The IC50 of Esonarimod is 117.5 μg/mL. Esonarimod does not affect cellular viability at these tested doses. Esonarimod has no direct effect on NOS activity in cell-free extracts of RAW264.7 cells.