产品
编 号：F748073
分子式：C25H30FN3O3S
分子量：471.59
分子式：C25H30FN3O3S
分子量：471.59
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 1953134-16-1
产品详情
生物活性：
GNE-502 is an orally active and potent degrader for estrogen receptor (ER). GNE-502 can be used for the research of breast cancer.
体内研究：
GNE-502 (10 and 100 mg/kg; p.o.) possesses sufficient oral exposure to be tested in a WT MCF7 tumor xenograft model.GNE-502 shows dose dependent tumor growth inhibition at 10 mg/kg and 30 mg/kg, with tumor stasis at 100 mg/kg.Animal Model:Mouse
Dosage:10 and 100 mg/kg (Pharmacokinetic Analysis)
Administration:p.o.; single dosage
Result:Possessed sufficient oral exposure to be tested in a WT MCF7 tumor xenograft model.
GNE-502 is an orally active and potent degrader for estrogen receptor (ER). GNE-502 can be used for the research of breast cancer.
体内研究：
GNE-502 (10 and 100 mg/kg; p.o.) possesses sufficient oral exposure to be tested in a WT MCF7 tumor xenograft model.GNE-502 shows dose dependent tumor growth inhibition at 10 mg/kg and 30 mg/kg, with tumor stasis at 100 mg/kg.Animal Model:Mouse
Dosage:10 and 100 mg/kg (Pharmacokinetic Analysis)
Administration:p.o.; single dosage
Result:Possessed sufficient oral exposure to be tested in a WT MCF7 tumor xenograft model.
产品资料
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