产品
编 号：F747621
分子式：C94H135N25O26S2
分子量：2095.36
分子式：C94H135N25O26S2
分子量：2095.36
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CAS No: 186526-28-3
产品详情
生物活性：
EPO mimetic peptide-1 (EMP-1), a 20 amino acid peptide. EPO mimetic peptide-1 stimulates cell proliferation, affects cell cycle and induces the production of reticulocytes in vivo.
体内研究：
EPO mimetic peptide-1 (1 and 2 mg; once) induces the production of reticulocytes over the background of endogenous in normal, untreated mice containing endogenous basal levels of EPO mice.
体外研究：
EPO mimetic peptide-1 shows inhibition of tracer 125I-labeled EPO binding with an IC50 value of 0.2 μM.EPO mimetic peptide-1 (0-50 mM; 48 h) stimulates proliferation of both TF-1 and B6Sut cells in a dose-dependent manner.EPO mimetic peptide-1 (1 and 10 μM) promots erythroid colony formation from human peripheral blood and murine bone marrow.EPO mimetic peptide-1 (10 μM; 10 min) induces the phosphorylation of proteins.EPO mimetic peptide-1 (1 and 10 μM; 0-18 h) affects cell cycle.
EPO mimetic peptide-1 (EMP-1), a 20 amino acid peptide. EPO mimetic peptide-1 stimulates cell proliferation, affects cell cycle and induces the production of reticulocytes in vivo.
体内研究：
EPO mimetic peptide-1 (1 and 2 mg; once) induces the production of reticulocytes over the background of endogenous in normal, untreated mice containing endogenous basal levels of EPO mice.
体外研究：
EPO mimetic peptide-1 shows inhibition of tracer 125I-labeled EPO binding with an IC50 value of 0.2 μM.EPO mimetic peptide-1 (0-50 mM; 48 h) stimulates proliferation of both TF-1 and B6Sut cells in a dose-dependent manner.EPO mimetic peptide-1 (1 and 10 μM) promots erythroid colony formation from human peripheral blood and murine bone marrow.EPO mimetic peptide-1 (10 μM; 10 min) induces the phosphorylation of proteins.EPO mimetic peptide-1 (1 and 10 μM; 0-18 h) affects cell cycle.
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