产品
编 号:F747610
分子式:C19H12FNO2
分子量:305.3
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5mg
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10mg
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25mg
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50mg
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生物活性:
hCYP3A4 Fluorogenic substrate 1 is a potrnt hCYP3A4 fluorogenic substrate with an Km value of 0.36 μM. hCYP3A4 Fluorogenic substrate 1 can be used for cell and in vivo imaging.

体内研究:
hCYP3A4 Fluorogenic substrate 1 (10 mg/kg; i.v.) 可用于体内成像。Animal Model:Male Sprague-Dawley rats
Dosage:10 mg/kg
Administration:I.v.
Result:Can be used as a probe substrate offers a highly efficient and easy-to-use approach for screening and characterizing hCYP3A4 inhibitors or time-dependent inactivators, which strongly facilitates hCYP3A4-mediated DDI studies.

体外研究:
hCYP3A4 Fluorogenic substrate 1 (compound F8) (20 μM; 30 min) 在活 Hep3B2 细胞和 Huh-7 细胞的绿色通道处显示出明亮的荧光信号。
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