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编 号:F747559
分子式:C25H21ClN2O6
分子量:480.9
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生物活性:
AMPK activator 8 (compound 2) is an AMP-activated protein kinase (AMPK)?activator with EC50s of 11, 27, 4, 2, and 4 nM for rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, rAMPK α2β2γ3, respectively. AMPK activator 8 can be used for the research of?type 2 diabetes.

体外研究:
AMPK activator 8 (compound 2) acts on rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ and rAMPK α2β2γ3 with the EC50 value of 11 nM, 27 nM, 4 nM, 2 nM and 4 nM, respectively.AMPK activator 8 (compound 2) affects cell viability.
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