产品
编 号：F747457
分子式：C26H40F6N10O11S2Zn
分子量：912.16
分子式：C26H40F6N10O11S2Zn
分子量：912.16
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 1831169-11-9
产品详情
生物活性：
UBA5-IN-1 (compound 8.5) is a selective UBA5 inhibitor with an IC50 value of 4.0 μM. UBA5-IN-1 inhibits cell proliferation of Sk-Luci6 cancer cells with high expression levels of UBA5.
体外研究：
UBA5-IN-1 (0.1-1000 μM) shows dose-dependent inhibition effect to UBA5 with an IC50 value of 4.0 μM, and inhibits UAE and NAE with IC50 values of 78.5 and 66.8 μM, respectively.UBA5-IN-1 (0-5 μM) inhibits UBA5 non-competitively with respect to ATP.UBA5-IN-1 (10 μM) shows no effect on ATP binding to human kinase.UBA5-IN-1 (0-50 μM; 72 h) effects cell proliferation of Sk-Luci6 cancer cells with high expression levels of UBA5.
UBA5-IN-1 (compound 8.5) is a selective UBA5 inhibitor with an IC50 value of 4.0 μM. UBA5-IN-1 inhibits cell proliferation of Sk-Luci6 cancer cells with high expression levels of UBA5.
体外研究：
UBA5-IN-1 (0.1-1000 μM) shows dose-dependent inhibition effect to UBA5 with an IC50 value of 4.0 μM, and inhibits UAE and NAE with IC50 values of 78.5 and 66.8 μM, respectively.UBA5-IN-1 (0-5 μM) inhibits UBA5 non-competitively with respect to ATP.UBA5-IN-1 (10 μM) shows no effect on ATP binding to human kinase.UBA5-IN-1 (0-50 μM; 72 h) effects cell proliferation of Sk-Luci6 cancer cells with high expression levels of UBA5.
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