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编 号:F747349
分子式:C57H79N13O12S2
分子量:1202.45
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生物活性:
BIM-23190, a somatostatin analog, a selective SSTR2 and SSTR5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly.

体内研究:
BIM-23190 (50 μg/mouse, twice a day) exhibits significant anti-tumor (C6 glioma) activity.Animal Model:Male athymic nude (nu/nu) mice, 5-6 wk old (C6 glioma).
Dosage:50 μg/mouse
Administration:Injected twice a day for 19 days.
Result:Significantly reduced the tumor growth rate.

体外研究:
BIM-23190 tends to mildly stimulate PRL secretion.
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