产品
编 号：F747244
分子式：C21H25N3O2S
分子量：383.51
分子式：C21H25N3O2S
分子量：383.51
产品类型
规格
价格
是否有货
结构图
CAS No: 1808389-92-5
产品详情
生物活性：
GABAA receptor agent 5 (compound 018) is a potent γ-GABAAR antagonist with an Ki of 0.020 μM. GABAA receptor agent 5 shows γ-GABAAR antagonist activity with low cellular membrane permeability.
体外研究：
GABAA receptor agent 5 (compound 018) shows antagonist activity with IC50s of 0.24, 0.088, 0.068, 0.33, 0.79, 0.32, 0.079, 0.051 μM for α1β2δ, α4β1δ, α4β2δ, α6β2δ, α1β2γ2, α2β2γ2, α3β2γ2, α5β2γ2 subtypes, respectively.
GABAA receptor agent 5 (compound 018) is a potent γ-GABAAR antagonist with an Ki of 0.020 μM. GABAA receptor agent 5 shows γ-GABAAR antagonist activity with low cellular membrane permeability.
体外研究：
GABAA receptor agent 5 (compound 018) shows antagonist activity with IC50s of 0.24, 0.088, 0.068, 0.33, 0.79, 0.32, 0.079, 0.051 μM for α1β2δ, α4β1δ, α4β2δ, α6β2δ, α1β2γ2, α2β2γ2, α3β2γ2, α5β2γ2 subtypes, respectively.
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