产品
编 号：F747178
分子式：C23H34N2O3
分子量：386.53
分子式：C23H34N2O3
分子量：386.53
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 1802909-49-4
产品详情
生物活性：
INCB059872 is a potent, orally active, selective and irreversible Lysine-Specific Demethylase 1 (LSD1) inhibitor. INCB059872 can be used for the research of myeloid leukemia.
体内研究：
INCB059872 (10 mg/kg; p.o.; 0, 4, or 6 days; C57BL/6J mice) makes single-cell RNA-seq revealing changes in bone marrow progenitor populations.Animal Model:Mice
Dosage:10 mg/kg
Administration:P.o.; 0, 4, or 6 days
Result:Single-cell RNA-seq revealed changes in bone marrow progenitor populations.
体外研究：
INCB059872 (25 nM; 48 hours; 293T cells) increases enhancer activity and gene expression.INCB059872 (25 nM; 24 hours; THP-1 cells) makes THP-1 show a growth defect within one cell doubling time or approximately 3 days. INCB059872 (THP-1 cells) regulates PRO-seq analysis identifies genes and enhancers.
INCB059872 is a potent, orally active, selective and irreversible Lysine-Specific Demethylase 1 (LSD1) inhibitor. INCB059872 can be used for the research of myeloid leukemia.
体内研究：
INCB059872 (10 mg/kg; p.o.; 0, 4, or 6 days; C57BL/6J mice) makes single-cell RNA-seq revealing changes in bone marrow progenitor populations.Animal Model:Mice
Dosage:10 mg/kg
Administration:P.o.; 0, 4, or 6 days
Result:Single-cell RNA-seq revealed changes in bone marrow progenitor populations.
体外研究：
INCB059872 (25 nM; 48 hours; 293T cells) increases enhancer activity and gene expression.INCB059872 (25 nM; 24 hours; THP-1 cells) makes THP-1 show a growth defect within one cell doubling time or approximately 3 days. INCB059872 (THP-1 cells) regulates PRO-seq analysis identifies genes and enhancers.
产品资料
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