产品
编 号：F747176
分子式：C20H18N4O7
分子量：426.38
分子式：C20H18N4O7
分子量：426.38
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CAS No: 1802891-20-8
产品详情
生物活性：
Human enteropeptidase-IN-1 (compound 6b) is a highly potent, orally active and low systemic exposure enteropeptidase inhibitor. Human enteropeptidase-IN-1 boosts the increase in fecal protein output, and exhibits potent body weight loss in diet-induced obese (DIO) rat model. Human enteropeptidase-IN-1 can be used for anti-obesity research.
体外研究：
Human enteropeptidase-IN-1 (compound 6b) has inhibitory activity against enteropeptidase with IC50(initial)* of 20 nM and IC50(app)** of 1.2 nM.(*IC50(initial) refers to the inhibitory activity of human enteropeptidase after 6 min of incubation with the enzyme, substrate, and compound.)(**IC50(app) refers to the apparent IC50 value after 120 min of incubation with the enzyme, substrate, and compound.)
Human enteropeptidase-IN-1 (compound 6b) is a highly potent, orally active and low systemic exposure enteropeptidase inhibitor. Human enteropeptidase-IN-1 boosts the increase in fecal protein output, and exhibits potent body weight loss in diet-induced obese (DIO) rat model. Human enteropeptidase-IN-1 can be used for anti-obesity research.
体外研究：
Human enteropeptidase-IN-1 (compound 6b) has inhibitory activity against enteropeptidase with IC50(initial)* of 20 nM and IC50(app)** of 1.2 nM.(*IC50(initial) refers to the inhibitory activity of human enteropeptidase after 6 min of incubation with the enzyme, substrate, and compound.)(**IC50(app) refers to the apparent IC50 value after 120 min of incubation with the enzyme, substrate, and compound.)
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