产品
编 号:F747152
分子式:C18H22Cl2N6S
分子量:425.38
产品类型
结构图
CAS No: 1801764-60-2
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产品详情
生物活性:
RMC-3943 is an allosteric SHP2 inhibitor (inhibition of full-length SHP2 in biochemical assay, IC50 = 2.19 nM).
体外研究:
RMC-3943 inhibits pERK in PC9 cells, with an IC50 of 35.5 nM.RMC-3943 (0-10 μM) produces a concentration-dependent inhibition of proliferation of SK-MEL-113 cells.