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编 号：F747043
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1mg
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CAS No: 179045-86-4
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生物活性：
Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation.
体内研究：
Basiliximab (CHI 621) (0.07 mg/rat; i.v.; once) decreases total placental natural killer cells in reduced uterine perfusion pressure (RUPP) rats.Animal Model:Timed-pregnant Sprague Dawley (SD) rats, reduced uterine perfusion pressure (RUPP) rat model of placental ischemia
Dosage:0.07 mg/rat
Administration:IV infusion, once
Result:Decreased total placental natural killer cells. Had no effect to lower MAP or improve pup weight and placental weight.
体外研究：
Basiliximab specifically inhibits T lymphocyte proliferation by binding to the IL-2Rα.Basiliximab binds only to activated lymphocytes and macrophages/monocytes. Basiliximab does not affect resting T lymphocytes that do not express IL-2Rα.
Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation.
体内研究：
Basiliximab (CHI 621) (0.07 mg/rat; i.v.; once) decreases total placental natural killer cells in reduced uterine perfusion pressure (RUPP) rats.Animal Model:Timed-pregnant Sprague Dawley (SD) rats, reduced uterine perfusion pressure (RUPP) rat model of placental ischemia
Dosage:0.07 mg/rat
Administration:IV infusion, once
Result:Decreased total placental natural killer cells. Had no effect to lower MAP or improve pup weight and placental weight.
体外研究：
Basiliximab specifically inhibits T lymphocyte proliferation by binding to the IL-2Rα.Basiliximab binds only to activated lymphocytes and macrophages/monocytes. Basiliximab does not affect resting T lymphocytes that do not express IL-2Rα.
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