产品
编 号:F076070
分子式:C17H16D3N3
分子量:268.37
产品类型
结构图
CAS No: 1216678-68-0
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生物活性:
Mirtazapine-d3 is a deuterium labeled Mirtazapine. Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors.
体内研究:
Mirtazapine (intraperitoneal injection; 10–50?mg/Kg; 14 days) treatment normalizes heart rate, breath rate, anxiety levels and eliminates the hopping behavior observed in MeCP2-null mice, leading to improved phenotypic score.Animal Model:MeCP2 null mice
Dosage:10-50 mg/Kg
Administration:Intraperitoneal injection; 10-50 mg/Kg; 14 days
Result:Restored the thickness of MeCP2-null mice somatosensory cortex, especially of layers II-III and VI.