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编 号:F746926
分子式:C157H253N53O42
分子量:3555.02
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生物活性:
[Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) is a synthetic PACAP 1-27 (HY-P0176) analogue with relaxant effect.

体外研究:
[Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) (0.1 μM; 0-5 h) causes longer acting smooth-muscle relaxation than does the original PACAP 1-27 in human bronchi in vitro.[Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (0.3-3 μM; 0-6 h) causes concentration-dependent relaxation with a very similar maximum relaxant effect and potency in the guinea-pig trachea.
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