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编 号:F746783
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CAS No: 1708936-80-4
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生物活性:
Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats.
体内研究:
Frunevetmab (1.0-2.8mg/kg;皮下注射;第 0、28 和 56 天) 对患有自然发生的骨关节炎疼痛和相关的行动障碍和残疾的猫显示出积极的处理效果。Animal Model:Cats with naturally-occurring OA pain and associated mobility impairment and disability
Dosage:1.0-2.8?mg/kg
Administration:s.c; 3 times at 28-day intervals; on days 0, 28, and 56
Result:Reliefed the pain from osteoarthritis in cats.
体外研究:
Frunevetmab (NV-02) 以高亲和力和效力中和 NGF,并且不结合补体。