产品
编 号:F746586
分子式:C36H46N4O5
分子量:614.77
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1mg
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5mg
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10mg
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生物活性:
SCO-267 is an allosteric GPR40 full agonist. SCO-267 can be used for the research of chronic diseases including diabetes.

体内研究:
SCO-267 (1 or 10 mg/kg; p.o.) improves insulin sensitivity and exerts sustained glucose-lowering effect.Animal Model:N-STZ rats
Dosage:1 or 10 mg/kg
Administration:P.o.;
Result:Improved insulin sensitivity and exerted sustained glucose-lowering effect.

体外研究:
SCO-267 (CHO cells) activates the Gαq, Gαs, and Gα12/13 pathways and β-Arrestin Recruitment. SCO-267 is allosteric with fasiglifam and an endogenous ligand.
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