产品
编 号:F746555
分子式:C17H28N2O
分子量:276.42
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
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询价
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产品详情
生物活性:
UNC3474 is a small molecule ligand, binding with 53BP1. UNC3474 binds the aromatic methyl-lysine binding cage of 53BP1TT, with a dissociation constant (Kd) of 1.0?±?0.3 μM. UNC3474 inhibits the recruitment of 53BP1 to DSBs by stabilizing a pre-existing autoinhibited state of 53BP1 in cells.

体外研究:
与 WT 53BP1TT 不同,53BP1TT-PN 不会与 UNC3474 相互作用。
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