产品
编 号:F746504
分子式:C19H17F2N3O4
分子量:389.35
产品类型
结构图
CAS No: 1643462-93-4
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产品详情
生物活性:
PW0464, a nanomolar potent complete G protein biased ligand, is a noncatechol D1R agonist, with an EC50 of 5.8 nM (Gs-cAMP).
体外研究:
PW0464 (compound 24) is found to elicit complete G protein bias, showing no activity for D1R-mediated β-arrestin recruitment.PW0464 (compound 24), the non-catechol agonist, forms bonds with S1985.42 and S2025.46 via its fluorine atom.