产品
编 号:F746493
分子式:C20H21ClN2O3S
分子量:404.91
产品类型
结构图
CAS No: 1642602-54-7
联系客服
产品详情
生物活性:
Leramistat (HMC-C-01-A; MBS2320) is a mitochondrial complex 1 inhibitor, involving in cell metabolism immune metabolism regulation. Leramistat also inhibits ATP production in Thp1 human monocytes (IC50: 0.63 μM). Leramistat inhibits atopic dermatitis and other skin diseases autoimmune diseases, inflammatory diseases, cancer; and also inhibits osteoclast mediated disease.
体外研究:
Leramistat 在大鼠肝细胞中的稳定性一般,半衰期为 7 min,在人肝细胞中的半衰期为 154 min。