产品
编 号:F746468
分子式:C32H51N7O8
分子量:661.79
产品类型
结构图
CAS No: 1639303-73-3
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产品详情
生物活性:
Odatroltide, as a nanoscale P-selectin inhibitor, is a nano-delivery system of 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to target the thrombus.
体内研究:
Odatroltide (0.01 nmol/kg) lyses the thrombus and inhibits thrombosis with a minimal.
体外研究:
Odatroltide (1 nM) effectively down-regulates P-selectin expression. DHDMIQK(KAP) effectively inhibits platelet aggregation via down-regulating the expression of P-selectin. Odatroltide effectively inhibits platelet aggregations induced by TH, AA, ADP and PAF, which are correlated with the downregulation of P-selectin expression and with the scavenging of the free radicals.