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编 号:F746423
分子式:C58H104N20O18S
分子量:1401.63
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结构图
CAS No: 163815-24-5
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生物活性:
SV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus.
体外研究:
SV40 large tumor-antigen (T-ag) nuclear import is enhanced by the protein kinase CK2 (CK2) site (Ser111Ser112) flanking the nuclear localization sequence (NLS). T-ag NLS can enhance nuclear import, despite the fact that PK-C has been shown to inhibit nuclear import of proteins such as lamin B2.