产品
编 号:F746280
分子式:C38H46N4O18
分子量:846.79
产品类型
结构图
CAS No: 1627600-90-1
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产品详情
生物活性:
Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition.
体外研究:
Antitumor agent-63 (Compound 40) shows cytotoxicity activities with IC50 values of 1.2, 0.8, 30.5 and >100 μM against HepG2, HCT-116, SW1990 and HEK-293, respectively.