产品
编 号:F746147
分子式:C30H35Cl2N3O9
分子量:652.52
产品类型
结构图
CAS No: 161511-45-1
联系客服
产品详情
生物活性:
SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1. SDZ 224-015 possesses anti-COVID-19 activity, targeting Mpro (IC50 of 30 nM).
体内研究:
SDZ 224-015 (0.3-300 μg/kg) potently reduces carrageenin-induced paw oedema.SDZ 224-015 (0.2-5 mg/kg, p.o.) displays analgesic activity in the Randall-Selitto yeast-inflamed paw pressure test, significant at a dose of 1 mg/kg.